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FAS-ASSOCIATED DEATH DOMAIN PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
Fas-Associated Death Domain Protein
Descriptor
Spanish
:
Proteína de Dominio de Muerte Asociada a Fas
Descriptor
Portuguese
:
Proteína de Domínio de Morte Associada a Fas
Tree Number:
D12.644.360.024.296.200
D12.644.360.024.500.124
D12.644.360.075.421.200
D12.776.157.057.024.200
D12.776.157.057.500.124
D12.776.476.024.375.550
D12.776.476.024.500.124
D12.776.476.075.421.200
Definition
English
:
A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR
CASPASES
such as
CASPASE 8
and
CASPASE 10
. Activation of
CASPASES
via interaction with this protein plays a role in the signaling cascade that leads to
APOPTOSIS.
History Note
English
:
2007(1995)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52311
Unique Identifier:
D053200
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS